Thursday, 2 June 2011
Small Bowel Follow Through and Small Bowel Obstruction
Apply with epilepsy in children in adults more frequently with partial seizures. From holinoblokatorov in Parkinson's disease and parkinsonism used trihexyphenidyl (tsiklodol), biperiden, which block Mholinoretseptor neostriatum and inhibit the stimulating effects of cholinergic neurons. Contraindicated in angle-closure glaucoma. In addition, the excitation of opioid receptors is activated K + channels, leading to membrane hyperpolarization of neurons. To reduce these side effects levodopa used together with inhibitors DOFAdekarboksilazy that do not stern into Non-Specific Urethritis CNS - carbidopa or benserazide. Pharmacological properties of opium are mainly determined by morphine, which in opium contains about 10%. Stimulates the release of GABA. Substances that stimulate opioid receptors differ in stimulating action. Selegiline increases the efficiency and duration of levodopa. However, means stern turning off the anesthesia and consciousness and other kinds of sensitivity. In appointing the inside is less effective due to low bioavailability (24%). Levodopa improves the quality of life in patients with Parkinson's disease, but does not slow disease progression (Continued decrease in the number of dopaminergic neurons in the substantia nigra). Secrete p (mu), k (kappa) and 8 (delta) receptors (Table. To eliminate the pain is also used local anesthetics. Axons of dopaminergic neurons in the substantia nigra terminate in the neostriatum and isolated as inhibitory neurotransmitter dopamine, which, acting on D2-retseptor, exerts inhibitory effects on stern neurons neostriatum 2. Stimulating postsynaptic opioid receptors, morphine activates K + channels, causing hyperpolarization of the postsynaptic membrane and thus preventing the action of neurotransmitters stern . Used for the prevention of partial seizures and tonikoklonicheskih. Effective with partial seizures. Assign inside. Amantadine (midantan) promotes the release of dopamine from the dopaminergic fiber endings and inhibits the stimulating effect glutamic acid on cholinergic neurons of the neostriatum (blocks NMDAretseptor). Nalbuphine butorphanol Pentazocine include full agonists’ opioid receptors and produce: phenanthrene derivatives - morphine, codeine, phenylpiperidine derivatives - trimeperidin, fentanyl, derivative fenilgeptilamina - methadone. Levodopa stern isomer of DOPA) - one of the most effective antiparkinsonian drugs. Parkinson's disease is the destruction of much of the dopaminergic stern in the black substance and thus weakens their inhibitory effect on cholinergic neurons of the neostriatum. Opium preparations have long been used for severe pain, anxiety, insomnia, as antitussives, and diarrhea. Appointment of levodopa in higher doses eliminates bradykinesia and rigidity, but causes dyskinesia (Involuntary movement of face, extremities), reminiscent of dyskinesia in Huntington's chorea. Inactivation levodopa in the periphery reduces the entacapone, which inhibits the COMT and thereby prevents Ometilirovaniyu levodopa. Lamotrigine blocks Na + channels in the presynaptic membrane of glutamatergic synapses and reduces the release of glutamic acid. From other antiepileptic drugs used gabapentin, lamotrigine, clonazepam. Analgesics - a substance that selectively reduce or eliminate the feeling of pain does not affect other kinds of sensitivity and do not depress consciousness. Thus, for the treatment of disease Parkinson's and Parkinson's disease need to either increase dopaminergic influence, or reduce the effects of cholinergic neurons. Morphine is a little lipo and poorly crosses the blood-brain barrier.
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